Knockdown of PKM2 Suppresses Tumor Growth and Invasion in Lung Adenocarcinoma

Knockdown of PKM2 Suppresses Tumor Growth and Invasion in Lung Adenocarcinoma

Accumulating evidence shows that activity of the pyruvate kinase M2 (PKM2) isoform is closely related to tumorigenesis. In this study, we investigated the relationship betweenPKM2 expression, tumor invasion, and the prognosis of patients with lung adenocarcinoma. We retrospectively analyzed 65 cases...

Full description

Bibliographic Details
Main Authors: Hong Sun, Anyou Zhu, Lunjun Zhang, Jie Zhang, Zhengrong Zhong, Fengchao Wang
Format: Article
Language:English
Published: MDPI AG 2015-10-01
Series:International Journal of Molecular Sciences
Subjects:
lung adenocarcinoma
pyruvate kinase M2
glycolysis
fatty acid synthesis
invasion
Online Access:http://www.mdpi.com/1422-0067/16/10/24574

Internet

http://www.mdpi.com/1422-0067/16/10/24574

Similar Items