Fabrication of a Thermosensitive In Situ Gel Nanoemulsion for Nose to Brain Delivery of Temozolomide

In this study, a thermosensitive in situ gel nanoemulsion was formulated by a low energy method for intranasal delivery of temozolomide to bypass the blood-brain barrier and optimize chemotherapy for glioblastoma. Various amounts of Labrasol, Transcutol®P, and Triacetin were chosen as nanoemulsion c...

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Bibliographic Details
Main Authors: Masoumeh Bayanati, Abolfazl Ghafouri Khosroshahi, Maryam Alvandi, Mohammad Mehdi Mahboobian
Format: Article
Language:English
Published: Hindawi Limited 2021-01-01
Series:Journal of Nanomaterials
Online Access:http://dx.doi.org/10.1155/2021/1546798