A 3D polyhedral metal–organic framework as drug carrier for controllable release

A new fabrication of {[H3O][Cu6(tpta)3(DMA)4(COO)]∙12H2O∙7DMA} (1) was used as a drug vehicle of 5-fluorouracil (5-FU) for drug delivery. The incorporation of the drug 5-FU into the 1 was around 47.3 wt% per gram of dehydrated 1. Cargo release behavior and material degradation profile were also inve...

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Bibliographic Details
Main Authors: E. H. Zhou, R. Wang, J. Wu, S. W. Qiu, J. Q. Liu, H. R. Zhong, H. D. Zeng, J. W. Xu, J. C. Jin
Format: Article
Language:English
Published: Chemical Society of Ethiopia 2018-01-01
Series:Bulletin of the Chemical Society of Ethiopia
Subjects:
Online Access:https://www.ajol.info/index.php/bcse/article/view/165350