Evaluating somatic tumor mutation detection without matched normal samples

Evaluating somatic tumor mutation detection without matched normal samples

Abstract Background Observations of recurrent somatic mutations in tumors have led to identification and definition of signaling and other pathways that are important for cancer progression and therapeutic targeting. As tumor cells contain both an individual’s inherited genetic variants and somatic...

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Bibliographic Details
Main Authors: Jamie K. Teer, Yonghong Zhang, Lu Chen, Eric A. Welsh, W. Douglas Cress, Steven A. Eschrich, Anders E. Berglund
Format: Article
Language:English
Published: BMC 2017-09-01
Series:Human Genomics
Subjects:
Somatic mutation
Cancer genomics
Next-generation sequencing
Precision medicine
Online Access:http://link.springer.com/article/10.1186/s40246-017-0118-2

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http://link.springer.com/article/10.1186/s40246-017-0118-2

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