(1,3)-β-D-glucan-based diagnosis of invasive Candida infection versus culture-based diagnosis in patients with sepsis and with an increased risk of invasive Candida infection (CandiSep): study protocol for a randomized controlled trial

(1,3)-β-D-glucan-based diagnosis of invasive Candida infection versus culture-based diagnosis in patients with sepsis and with an increased risk of invasive Candida infection (CandiSep): study protocol for a randomized controlled trial

Abstract Background The time to diagnosis of invasive Candida infection (ICI) is often too long to initiate timely antifungal therapy in patients with sepsis. Elevated serum (1,3)-β-D-glucan (BDG) concentrations have a high diagnostic sensitivity for detecting ICI. However, the clinical significance...

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Bibliographic Details
Main Authors: Frank Bloos, Jürgen Held, Peter Schlattmann, Nicole Brillinger, Oliver Kurzai, Oliver A. Cornely, Daniel Thomas-Rüddel
Format: Article
Language:English
Published: BMC 2018-09-01
Series:Trials
Subjects:
Sepsis
Septic shock
Invasive Candida infection
Early antifungal therapy
(1,3)-β-D-glucan
Biomarker
Online Access:http://link.springer.com/article/10.1186/s13063-018-2868-0

Internet

http://link.springer.com/article/10.1186/s13063-018-2868-0

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