Intestinal Permeation Enhancers for Oral Delivery of Macromolecules: A Comparison between Salcaprozate Sodium (SNAC) and Sodium Caprate (C<sub>10</sub>)

Intestinal Permeation Enhancers for Oral Delivery of Macromolecules: A Comparison between Salcaprozate Sodium (SNAC) and Sodium Caprate (C<sub>10</sub>)

Salcaprozate sodium (SNAC) and sodium caprate (C<sub>10</sub>) are two of the most advanced intestinal permeation enhancers (PEs) that have been tested in clinical trials for oral delivery of macromolecules. Their effects on intestinal epithelia were studied for over 30 years, yet there...

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Bibliographic Details
Main Authors: Caroline Twarog, Sarinj Fattah, Joanne Heade, Sam Maher, Elias Fattal, David J. Brayden
Format: Article
Language:English
Published: MDPI AG 2019-02-01
Series:Pharmaceutics
Subjects:
oral macromolecule delivery
oral peptides
sodium caprate
salcaprozate sodium
epithelial permeability
epithelial transport
Online Access:https://www.mdpi.com/1999-4923/11/2/78

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https://www.mdpi.com/1999-4923/11/2/78

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