A five-year review of vertical HIV transmission in a specialized service: cross-sectional study

ABSTRACT CONTEXT AND OBJECTIVE: Healthcare professionals need to instill the process of prevention, control and treatment of people infected with HIV into care practice. Through maintaining preventive treatment among HIV-infected pregnant women, it has been demonstrated that prophylactic antiretro...

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Main Authors: Izabel Cristina Hoffmann, Wendel Mombaque dos Santos, Stela Maris de Mello Padoin, Sonia Maria Oliveira de Barros
Format: Article
Language:English
Published: Associação Paulista de Medicina
Series:São Paulo Medical Journal
Subjects:
HIV
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31802016005012102&lng=en&tlng=en
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spelling doaj-622fc1a6a53a46b7a44f9de70a9d620b2020-11-24T22:53:33ZengAssociação Paulista de MedicinaSão Paulo Medical Journal1806-9460010.1590/1516-3180.2016.0139140616S1516-31802016005012102A five-year review of vertical HIV transmission in a specialized service: cross-sectional studyIzabel Cristina HoffmannWendel Mombaque dos SantosStela Maris de Mello PadoinSonia Maria Oliveira de BarrosABSTRACT CONTEXT AND OBJECTIVE: Healthcare professionals need to instill the process of prevention, control and treatment of people infected with HIV into care practice. Through maintaining preventive treatment among HIV-infected pregnant women, it has been demonstrated that prophylactic antiretroviral therapy, scheduled cesarean section and the prohibition of breastfeeding significantly reduce vertical HIV transmission. This study aimed to assess the rates of vertical HIV transmission in a specialized service and identify the factors associated with it. DESIGN AND SETTING: Cross-sectional study developed at the University Hospital of Santa Maria (RS), Brazil. METHODS: A cross-sectional study was conducted on a sample of 198 notification forms and medical records of HIV-positive pregnant women and exposed children. RESULTS: The vertical transmission rate was 2.4%, and three children had been infected by vertical HIV transmission. The statistically significant risk factor was the use of injectable drugs. Delayed reporting of pregnancy, absence of antiretroviral therapy during pregnancy, lack of proper prenatal care, incapacity to perform viral load detection tests and CD4+ T cell counts and obstetric and maternal clinical complications were reported. CONCLUSIONS: The vertical transmission rate was high and the recommended intervention measures were not adopted in full. Adequate prophylactic measures need to be implemented in HIV-positive pregnant women prenatally and during the antenatal, delivery and postpartum periods.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31802016005012102&lng=en&tlng=enHIVInfectious disease transmission, verticalWomen's healthChild healthHospital records
collection DOAJ
language English
format Article
sources DOAJ
author Izabel Cristina Hoffmann
Wendel Mombaque dos Santos
Stela Maris de Mello Padoin
Sonia Maria Oliveira de Barros
spellingShingle Izabel Cristina Hoffmann
Wendel Mombaque dos Santos
Stela Maris de Mello Padoin
Sonia Maria Oliveira de Barros
A five-year review of vertical HIV transmission in a specialized service: cross-sectional study
São Paulo Medical Journal
HIV
Infectious disease transmission, vertical
Women's health
Child health
Hospital records
author_facet Izabel Cristina Hoffmann
Wendel Mombaque dos Santos
Stela Maris de Mello Padoin
Sonia Maria Oliveira de Barros
author_sort Izabel Cristina Hoffmann
title A five-year review of vertical HIV transmission in a specialized service: cross-sectional study
title_short A five-year review of vertical HIV transmission in a specialized service: cross-sectional study
title_full A five-year review of vertical HIV transmission in a specialized service: cross-sectional study
title_fullStr A five-year review of vertical HIV transmission in a specialized service: cross-sectional study
title_full_unstemmed A five-year review of vertical HIV transmission in a specialized service: cross-sectional study
title_sort five-year review of vertical hiv transmission in a specialized service: cross-sectional study
publisher Associação Paulista de Medicina
series São Paulo Medical Journal
issn 1806-9460
description ABSTRACT CONTEXT AND OBJECTIVE: Healthcare professionals need to instill the process of prevention, control and treatment of people infected with HIV into care practice. Through maintaining preventive treatment among HIV-infected pregnant women, it has been demonstrated that prophylactic antiretroviral therapy, scheduled cesarean section and the prohibition of breastfeeding significantly reduce vertical HIV transmission. This study aimed to assess the rates of vertical HIV transmission in a specialized service and identify the factors associated with it. DESIGN AND SETTING: Cross-sectional study developed at the University Hospital of Santa Maria (RS), Brazil. METHODS: A cross-sectional study was conducted on a sample of 198 notification forms and medical records of HIV-positive pregnant women and exposed children. RESULTS: The vertical transmission rate was 2.4%, and three children had been infected by vertical HIV transmission. The statistically significant risk factor was the use of injectable drugs. Delayed reporting of pregnancy, absence of antiretroviral therapy during pregnancy, lack of proper prenatal care, incapacity to perform viral load detection tests and CD4+ T cell counts and obstetric and maternal clinical complications were reported. CONCLUSIONS: The vertical transmission rate was high and the recommended intervention measures were not adopted in full. Adequate prophylactic measures need to be implemented in HIV-positive pregnant women prenatally and during the antenatal, delivery and postpartum periods.
topic HIV
Infectious disease transmission, vertical
Women's health
Child health
Hospital records
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31802016005012102&lng=en&tlng=en
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