Extended disorder at the cell surface: The conformational landscape of the ectodomains of syndecans

Syndecans are membrane proteoglycans regulating extracellular matrix assembly, cell adhesion and signaling. Their ectodomains can be shed from the cell surface, and act as paracrine and autocrine effectors or as competitors of full-length syndecans. We report the first biophysical characterization o...

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Bibliographic Details
Main Authors: Frank Gondelaud, Mathilde Bouakil, Aurélien Le Fèvre, Adriana Erica Miele, Fabien Chirot, Bertrand Duclos, Adam Liwo, Sylvie Ricard-Blum
Format: Article
Language:English
Published: Elsevier 2021-12-01
Series:Matrix Biology Plus
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2590028521000259