In Vivo Induction of Myeloid Suppressor Cells and CD4Foxp3 T Regulatory Cells Prolongs Skin Allograft Survival in Mice

Natural CD4 + Foxp3 + T regulatory (Treg) cells can promote transplantation acceptance across major histocompatibility complex (MHC) barriers, while myeloid-derived suppressor cells (MDSCs) inhibit effector T-cell responses in tumor-bearing mice. One outstanding issue is whether combining the potent...

Full description

Bibliographic Details
Main Authors: D. Adeegbe, P. Serafini, V. Bronte, A. Zoso, C. Ricordi, L. Inverardi
Format: Article
Language:English
Published: SAGE Publishing 2011-07-01
Series:Cell Transplantation
Online Access:https://doi.org/10.3727/096368910X540621