Modeling psychiatric disorders through reprogramming

Psychiatric disorders, including autism spectrum disorders and schizophrenia, are extremely heritable complex genetic neurodevelopmental disorders. It is now possible to directly reprogram fibroblasts from psychiatric patients into human induced pluripotent stem cells (hiPSCs) and subsequently diffe...

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Bibliographic Details
Main Authors: Kristen J. Brennand, Fred H. Gage
Format: Article
Language:English
Published: The Company of Biologists 2012-01-01
Series:Disease Models & Mechanisms
Online Access:http://dmm.biologists.org/content/5/1/26

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