Synchronous primary ovarian and endometrial cancers: a series of cases and a review of literature

Synchronous cancers account for 0.7-1.8% of all gynecologic cancers. Among them, synchronous ovarian and endometrial cancers are predominant (40-53%). Patients with synchronous cancers have better prognosis than those with single disseminated cancer. We present 10 patients with synchronous ovarian a...

Full description

Bibliographic Details
Main Authors: Sylwia Dębska-Szmich, Urszula Czernek, Magdalena Krakowska, Marta Frąckowiak, Agnieszka Zięba, Rafał Czyżykowski, Dominika Kulejewska, Piotr Potemski
Format: Article
Language:English
Published: Termedia Publishing House 2014-03-01
Series:Menopause Review
Subjects:
Online Access:http://www.termedia.pl/Synchronous-primary-ovarian-and-endometrial-cancers-a-series-of-cases-and-a-review-of-literature,4,22414,1,1.html
id doaj-62fd21b42f63482fadddb1550e43ed9d
record_format Article
spelling doaj-62fd21b42f63482fadddb1550e43ed9d2020-11-24T23:02:44ZengTermedia Publishing HouseMenopause Review1643-88762299-00382014-03-01131646910.5114/pm.2014.4108422414Synchronous primary ovarian and endometrial cancers: a series of cases and a review of literatureSylwia Dębska-SzmichUrszula CzernekMagdalena KrakowskaMarta FrąckowiakAgnieszka ZiębaRafał CzyżykowskiDominika KulejewskaPiotr PotemskiSynchronous cancers account for 0.7-1.8% of all gynecologic cancers. Among them, synchronous ovarian and endometrial cancers are predominant (40-53%). Patients with synchronous cancers have better prognosis than those with single disseminated cancer. We present 10 patients with synchronous ovarian and endometrial cancers who were treated at the Chemotherapy Department of the Medical University of Lodz in 2009-2013. The most often reported symptom of the disease was abnormal vaginal bleeding (6 patients). The range of the patients’ age was 48-62 and the median age was 56. Five patients had stage I of ovarian cancer, single patients had stage IIA, IIB and IIIB, 2 patients had stage IIIC. Three patients had I, 5 – II, and 2 – III stage of endometrial cancer. All patients had endometrioid type of endometrial cancer, 7 of them had also the same histological type of ovarian cancer. All patients had adjuvant chemotherapy because of ovarian cancer, none of them had adjuvant radiotherapy. One patient was lost to follow up. For other patients a median follow up was 13 months (range: 3-53 months). One patient experienced relapse, all patients are alive. Synchronous ovarian and endometrial cancers are usually diagnosed at an earlier stage, have lower histological grade and better prognosis than single cancers. The most common histological type of both endometrial and ovarian cancers is endometrioid carcinoma. The first symptoms reported by our patients and the course of the disease were concordant with data from the literature.http://www.termedia.pl/Synchronous-primary-ovarian-and-endometrial-cancers-a-series-of-cases-and-a-review-of-literature,4,22414,1,1.htmlsynchronous cancers ovarian cancer endometrial cancer endometrioid type adjuvant treatment
collection DOAJ
language English
format Article
sources DOAJ
author Sylwia Dębska-Szmich
Urszula Czernek
Magdalena Krakowska
Marta Frąckowiak
Agnieszka Zięba
Rafał Czyżykowski
Dominika Kulejewska
Piotr Potemski
spellingShingle Sylwia Dębska-Szmich
Urszula Czernek
Magdalena Krakowska
Marta Frąckowiak
Agnieszka Zięba
Rafał Czyżykowski
Dominika Kulejewska
Piotr Potemski
Synchronous primary ovarian and endometrial cancers: a series of cases and a review of literature
Menopause Review
synchronous cancers
ovarian cancer
endometrial cancer
endometrioid type
adjuvant treatment
author_facet Sylwia Dębska-Szmich
Urszula Czernek
Magdalena Krakowska
Marta Frąckowiak
Agnieszka Zięba
Rafał Czyżykowski
Dominika Kulejewska
Piotr Potemski
author_sort Sylwia Dębska-Szmich
title Synchronous primary ovarian and endometrial cancers: a series of cases and a review of literature
title_short Synchronous primary ovarian and endometrial cancers: a series of cases and a review of literature
title_full Synchronous primary ovarian and endometrial cancers: a series of cases and a review of literature
title_fullStr Synchronous primary ovarian and endometrial cancers: a series of cases and a review of literature
title_full_unstemmed Synchronous primary ovarian and endometrial cancers: a series of cases and a review of literature
title_sort synchronous primary ovarian and endometrial cancers: a series of cases and a review of literature
publisher Termedia Publishing House
series Menopause Review
issn 1643-8876
2299-0038
publishDate 2014-03-01
description Synchronous cancers account for 0.7-1.8% of all gynecologic cancers. Among them, synchronous ovarian and endometrial cancers are predominant (40-53%). Patients with synchronous cancers have better prognosis than those with single disseminated cancer. We present 10 patients with synchronous ovarian and endometrial cancers who were treated at the Chemotherapy Department of the Medical University of Lodz in 2009-2013. The most often reported symptom of the disease was abnormal vaginal bleeding (6 patients). The range of the patients’ age was 48-62 and the median age was 56. Five patients had stage I of ovarian cancer, single patients had stage IIA, IIB and IIIB, 2 patients had stage IIIC. Three patients had I, 5 – II, and 2 – III stage of endometrial cancer. All patients had endometrioid type of endometrial cancer, 7 of them had also the same histological type of ovarian cancer. All patients had adjuvant chemotherapy because of ovarian cancer, none of them had adjuvant radiotherapy. One patient was lost to follow up. For other patients a median follow up was 13 months (range: 3-53 months). One patient experienced relapse, all patients are alive. Synchronous ovarian and endometrial cancers are usually diagnosed at an earlier stage, have lower histological grade and better prognosis than single cancers. The most common histological type of both endometrial and ovarian cancers is endometrioid carcinoma. The first symptoms reported by our patients and the course of the disease were concordant with data from the literature.
topic synchronous cancers
ovarian cancer
endometrial cancer
endometrioid type
adjuvant treatment
url http://www.termedia.pl/Synchronous-primary-ovarian-and-endometrial-cancers-a-series-of-cases-and-a-review-of-literature,4,22414,1,1.html
work_keys_str_mv AT sylwiadebskaszmich synchronousprimaryovarianandendometrialcancersaseriesofcasesandareviewofliterature
AT urszulaczernek synchronousprimaryovarianandendometrialcancersaseriesofcasesandareviewofliterature
AT magdalenakrakowska synchronousprimaryovarianandendometrialcancersaseriesofcasesandareviewofliterature
AT martafrackowiak synchronousprimaryovarianandendometrialcancersaseriesofcasesandareviewofliterature
AT agnieszkazieba synchronousprimaryovarianandendometrialcancersaseriesofcasesandareviewofliterature
AT rafałczyzykowski synchronousprimaryovarianandendometrialcancersaseriesofcasesandareviewofliterature
AT dominikakulejewska synchronousprimaryovarianandendometrialcancersaseriesofcasesandareviewofliterature
AT piotrpotemski synchronousprimaryovarianandendometrialcancersaseriesofcasesandareviewofliterature
_version_ 1725635366570950656