Tumor-infiltrating T cells and PD-L1 expression in childhood malignant extracranial germ-cell tumors

Tumor-infiltrating T cells and PD-L1 expression in childhood malignant extracranial germ-cell tumors

Although pediatric malignant extracranial germ-cell tumors (meGCTs) are among the most chemosensitive solid tumors, a group of patients relapse and die of disease. To identify new markers predicting clinical outcome, we examined the prognostic relevance of tumor-infiltrating T lymphocytes (TILs) and...

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Bibliographic Details
Main Authors: Renata Boldrini, Maria Debora De Pasquale, Ombretta Melaiu, Marco Chierici, Giuseppe Jurman, Maria Chiara Benedetti, Nunzio C. Salfi, Aurora Castellano, Paola Collini, Cesare Furlanello, Vito Pistoia, Loredana Cifaldi, Monica Terenziani, Doriana Fruci
Format: Article
Language:English
Published: Taylor & Francis Group 2019-02-01
Series:OncoImmunology
Subjects:
tumor microenvironment
pediatric cancer
malignant extracranial germ-cell tumor
effector t cells
regulatory t cells
pd-1
pd-l1
immunohistochemistry
Online Access:http://dx.doi.org/10.1080/2162402X.2018.1542245

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