The pentapeptide RM-131 promotes food intake and adiposity in wildtype mice but not in mice lacking the ghrelin receptor

The pentapeptide RM-131 promotes food intake and adiposity in wildtype mice but not in mice lacking the ghrelin receptor

The gastrointestinal peptide hormone ghrelin is the endogenous ligand of the growth hormone secretagogue receptor (GHSR, a.k.a. ghrelin receptor, GHR). Currently, ghrelin is the only circulating peripheral hormone with the ability to promote a positive energy balance by stimulating food intake while...

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Bibliographic Details
Main Authors: Katrin eFischer, Brian eFinan, Christoffer eClemmensen, Lex H.T. van der Ploeg, Matthias H. Tschöp, Timo D. Müller
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-01-01
Series:Frontiers in Nutrition
Subjects:
Adiposity
Ghrelin
food intake
GHR
RM-131
GHSR1a
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnut.2014.00031/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnut.2014.00031/full

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