Absence of Rybp Compromises Neural Differentiation of Embryonic Stem Cells

Rybp (Ring1 and Yy1 Binding Protein) is a transcriptional regulator and member of the noncanonical polycomb repressive complex 1 with essential role in early embryonic development. We have previously described that alteration of Rybp dosage in mouse models induced striking neural tube defects (NTDs)...

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Bibliographic Details
Main Authors: Gergo Kovacs, Viktoria Szabo, Melinda K. Pirity
Format: Article
Language:English
Published: Hindawi Limited 2016-01-01
Series:Stem Cells International
Online Access:http://dx.doi.org/10.1155/2016/4034620

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