KChIP3 coupled to Ca2+ oscillations exerts a tonic brake on baseline mucin release in the colon

Regulated mucin secretion from specialized goblet cells by exogenous agonist-dependent (stimulated) and -independent (baseline) manner is essential for the function of the epithelial lining. Over extended periods, baseline release of mucin can exceed quantities released by stimulated secretion, yet...

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Bibliographic Details
Main Authors: Gerard Cantero-Recasens, Cristian M Butnaru, Miguel A Valverde, José R Naranjo, Nathalie Brouwers, Vivek Malhotra
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2018-10-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/39729