Influence of Polyplex Formation on the Performance of Star-Shaped Polycationic Transfection Agents for Mammalian Cells

Genetic modification (“transfection”) of mammalian cells using non-viral, synthetic agents such as polycations, is still a challenge. Polyplex formation between the DNA and the polycation is a decisive step in such experiments. Star-shaped polycations have been proposed as superior transfection agen...

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Bibliographic Details
Main Authors: Alexander Raup, Ullrich Stahlschmidt, Valérie Jérôme, Christopher V. Synatschke, Axel H. E. Müller, Ruth Freitag
Format: Article
Language:English
Published: MDPI AG 2016-06-01
Series:Polymers
Subjects:
Online Access:http://www.mdpi.com/2073-4360/8/6/224