Hyperpolarized Dihydroxyacetone Is a Sensitive Probe of Hepatic Gluconeogenic State

Hyperpolarized Dihydroxyacetone Is a Sensitive Probe of Hepatic Gluconeogenic State

Type II diabetes and pre-diabetes are widely prevalent among adults. Elevated serum glucose levels are commonly treated by targeting hepatic gluconeogenesis for downregulation. However, direct measurement of hepatic gluconeogenic capacity is accomplished only via tracer metabolism approaches that re...

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Bibliographic Details
Main Authors: Mukundan Ragavan, Marc A. McLeod, Anthony G. Giacalone, Matthew E. Merritt
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Metabolites
Subjects:
hyperpolarization
hepatic gluconeogenesis
dynamic nuclear polarization
diabetic liver
Online Access:https://www.mdpi.com/2218-1989/11/7/441

Internet

https://www.mdpi.com/2218-1989/11/7/441

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