A Novel Phenotype of Germline Pathogenic Variants in MAX: Concurrence of Pheochromocytoma and Ganglioneuroma in a Chinese Family and Literature Review

Background:MYC associated factor X (MAX) is a tumor suppressor gene and has been identified as one of the pathogenic genes of hereditary pheochromocytoma (PCC). To date, there have been no reports of ganglioneuroma (GN) with MAX variants.Case Presentation: The proband was a 45-years-old Chinese fema...

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Bibliographic Details
Main Authors: Xiaoyan Chang, Zelin Li, Xiaosen Ma, Yunying Cui, Shuchun Chen, Anli Tong
Format: Article
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Endocrinology
Online Access:https://www.frontiersin.org/article/10.3389/fendo.2020.00558/full