High PR3-ANCA positivity in a patient with chronic inflammatory demyelinating polyneuropathy

High PR3-ANCA positivity in a patient with chronic inflammatory demyelinating polyneuropathy

Proteinase 3 anti-neutrophil cytoplasmic antibody (PR3-ANCA) is reported to be highly specific to vasculitis compared to myeloperoxidase (MPO)-ANCA. We report a case of a 19-year-old woman with chronic inflammatory demyelinating polyneuropathy (CIDP) with high PR3-ANCA positivity. The patient respon...

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Bibliographic Details
Main Authors: Masanori Kurihara, Yu Kurata, Izumi Sugimoto, Yuki Hatanaka, Yasuhisa Sakurai
Format: Article
Language:English
Published: Elsevier 2017-03-01
Series:eNeurologicalSci
Subjects:
PR3-anti-neutrophil cytoplasmic antibody (PR3-ANCA)
Chronic inflammatory demyelinating polyneuropathy (CIDP)
Vasculitic neuropathy
Online Access:http://www.sciencedirect.com/science/article/pii/S2405650216300314
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spelling doaj-65f9f16262664f88818fe9710c0024b82020-11-24T20:51:24ZengElseviereNeurologicalSci2405-65022017-03-016C4510.1016/j.ensci.2016.10.001High PR3-ANCA positivity in a patient with chronic inflammatory demyelinating polyneuropathyMasanori Kurihara0Yu Kurata1Izumi Sugimoto2Yuki Hatanaka3Yasuhisa Sakurai4Department of Neurology, Mitsui Memorial Hospital, Tokyo, JapanDepartment of Nephrology, Mitsui Memorial Hospital, Tokyo, JapanDepartment of Neurology, Mitsui Memorial Hospital, Tokyo, JapanDepartment of Neurology, Mitsui Memorial Hospital, Tokyo, JapanDepartment of Neurology, Mitsui Memorial Hospital, Tokyo, JapanProteinase 3 anti-neutrophil cytoplasmic antibody (PR3-ANCA) is reported to be highly specific to vasculitis compared to myeloperoxidase (MPO)-ANCA. We report a case of a 19-year-old woman with chronic inflammatory demyelinating polyneuropathy (CIDP) with high PR3-ANCA positivity. The patient responded well to intravenous immunoglobulin plus oral steroid, and showed no signs of systemic vasculitis during the subsequent 10 months of follow-up. Our present case suggests that CIDP may accompany high PR3-ANCA levels, which should be differentiated from axonal neuropathy due to vasculitis.http://www.sciencedirect.com/science/article/pii/S2405650216300314PR3-anti-neutrophil cytoplasmic antibody (PR3-ANCA)Chronic inflammatory demyelinating polyneuropathy (CIDP)Vasculitic neuropathy
collection DOAJ
language English
format Article
sources DOAJ
author Masanori Kurihara
Yu Kurata
Izumi Sugimoto
Yuki Hatanaka
Yasuhisa Sakurai
spellingShingle Masanori Kurihara
Yu Kurata
Izumi Sugimoto
Yuki Hatanaka
Yasuhisa Sakurai
High PR3-ANCA positivity in a patient with chronic inflammatory demyelinating polyneuropathy
eNeurologicalSci
PR3-anti-neutrophil cytoplasmic antibody (PR3-ANCA)
Chronic inflammatory demyelinating polyneuropathy (CIDP)
Vasculitic neuropathy
author_facet Masanori Kurihara
Yu Kurata
Izumi Sugimoto
Yuki Hatanaka
Yasuhisa Sakurai
author_sort Masanori Kurihara
title High PR3-ANCA positivity in a patient with chronic inflammatory demyelinating polyneuropathy
title_short High PR3-ANCA positivity in a patient with chronic inflammatory demyelinating polyneuropathy
title_full High PR3-ANCA positivity in a patient with chronic inflammatory demyelinating polyneuropathy
title_fullStr High PR3-ANCA positivity in a patient with chronic inflammatory demyelinating polyneuropathy
title_full_unstemmed High PR3-ANCA positivity in a patient with chronic inflammatory demyelinating polyneuropathy
title_sort high pr3-anca positivity in a patient with chronic inflammatory demyelinating polyneuropathy
publisher Elsevier
series eNeurologicalSci
issn 2405-6502
publishDate 2017-03-01
description Proteinase 3 anti-neutrophil cytoplasmic antibody (PR3-ANCA) is reported to be highly specific to vasculitis compared to myeloperoxidase (MPO)-ANCA. We report a case of a 19-year-old woman with chronic inflammatory demyelinating polyneuropathy (CIDP) with high PR3-ANCA positivity. The patient responded well to intravenous immunoglobulin plus oral steroid, and showed no signs of systemic vasculitis during the subsequent 10 months of follow-up. Our present case suggests that CIDP may accompany high PR3-ANCA levels, which should be differentiated from axonal neuropathy due to vasculitis.
topic PR3-anti-neutrophil cytoplasmic antibody (PR3-ANCA)
Chronic inflammatory demyelinating polyneuropathy (CIDP)
Vasculitic neuropathy
url http://www.sciencedirect.com/science/article/pii/S2405650216300314
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AT yukurata highpr3ancapositivityinapatientwithchronicinflammatorydemyelinatingpolyneuropathy
AT izumisugimoto highpr3ancapositivityinapatientwithchronicinflammatorydemyelinatingpolyneuropathy
AT yukihatanaka highpr3ancapositivityinapatientwithchronicinflammatorydemyelinatingpolyneuropathy
AT yasuhisasakurai highpr3ancapositivityinapatientwithchronicinflammatorydemyelinatingpolyneuropathy
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