Comparison of the Sulfonamide Inhibition Profiles of the α-Carbonic Anhydrase Isoforms (SpiCA1, SpiCA2 and SpiCA3) Encoded by the Genome of the Scleractinian Coral Stylophora pistillata

Comparison of the Sulfonamide Inhibition Profiles of the α-Carbonic Anhydrase Isoforms (SpiCA1, SpiCA2 and SpiCA3) Encoded by the Genome of the Scleractinian Coral Stylophora pistillata

The ubiquitous metalloenzymes carbonic anhydrases (CAs, EC 4.2.1.1) are responsible for the reversible hydration of CO2 to bicarbonate (HCO3−) and protons (H+). Bicarbonate may subsequently generate carbonate used in many functional activities by marine organisms. CAs play a crucial role i...

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Bibliographic Details
Main Authors: Sonia Del Prete, Silvia Bua, Fatmah A. S. Alasmary, Zeid AlOthman, Sylvie Tambutté, Didier Zoccola, Claudiu T. Supuran, Clemente Capasso
Format: Article
Language:English
Published: MDPI AG 2019-03-01
Series:Marine Drugs
Subjects:
carbonic anhydrases
sulfonamides
CA isoforms
biomineralization
corals CAs
recombinant enzyme
Online Access:http://www.mdpi.com/1660-3397/17/3/146

Internet

http://www.mdpi.com/1660-3397/17/3/146

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