Selective In Vitro Propagation of Nephron Progenitors Derived from Embryos and Pluripotent Stem Cells

Nephron progenitors in the embryonic kidney propagate while generating differentiated nephrons. However, in mice, the progenitors terminally differentiate shortly after birth. Here, we report a method for selectively expanding nephron progenitors in vitro in an undifferentiated state. Combinatorial...

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Bibliographic Details
Main Authors: Shunsuke Tanigawa, Atsuhiro Taguchi, Nirmala Sharma, Alan O. Perantoni, Ryuichi Nishinakamura
Format: Article
Language:English
Published: Elsevier 2016-04-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124716303655