The Fitness Cost of Fluoride Resistance for Different Streptococcus mutans Strains in Biofilms

The cariogenic bacterium Streptococcus mutans can develop stable resistance to fluoride through chromosomal mutations in vitro. Fluoride-resistant S. mutans has seldom been isolated in clinical settings, despite the wide application of fluoride in oral-care products. One explanation is that the fluo...

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Bibliographic Details
Main Authors: Yanling Cai, Ying Liao, Bernd W. Brandt, Xi Wei, Hongyan Liu, Wim Crielaard, Cor Van Loveren, Dong Mei Deng
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-08-01
Series:Frontiers in Microbiology
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fmicb.2017.01630/full