Inhibition of Type IV Secretion Activity and Growth of Helicobacter pylori by Cisplatin and Other Platinum Complexes

Inhibition of Type IV Secretion Activity and Growth of Helicobacter pylori by Cisplatin and Other Platinum Complexes

Type IV secretion systems are protein secretion machineries that are frequently used by pathogenic bacteria to inject their virulence factors into target cells of their respective hosts. In the case of the human gastric pathogen Helicobacter pylori, the cytotoxin-associated gene (Cag) type IV secret...

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Bibliographic Details
Main Authors: Clara Lettl, Franziska Schindele, Giambattista Testolin, Alexander Bär, Tobias Rehm, Mark Brönstrup, Rainer Schobert, Ursula Bilitewski, Rainer Haas, Wolfgang Fischer
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-12-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Helicobacter pylori
type IV secretion system
Cag
cisplatin
protein secretion
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2020.602958/full

Internet

https://www.frontiersin.org/articles/10.3389/fcimb.2020.602958/full

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