Statin treatment in hypercholesterolemic men does not attenuate angiotensin II-induced venoconstriction.

Statin treatment in hypercholesterolemic men does not attenuate angiotensin II-induced venoconstriction.

Experimental studies suggested that statins attenuate vascular AT1 receptor responsiveness. Moreover, the augmented excessive pressor response to systemic angiotensin II infusions in hypercholesterolemic patients was normalized with statin treatment. In 12 hypercholesterolemic patients, we tested th...

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Bibliographic Details
Main Authors: Christoph Schindler, Kristina Guenther, Cosima Hermann, Carlos M Ferrario, Christoph Schroeder, Sven Haufe, Jens Jordan, Wilhelm Kirch
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4179232?pdf=render

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http://europepmc.org/articles/PMC4179232?pdf=render

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