Early circulating tumour DNA kinetics measured by ultra-deep next-generation sequencing during radical radiotherapy for non-small cell lung cancer: a feasibility study

Early circulating tumour DNA kinetics measured by ultra-deep next-generation sequencing during radical radiotherapy for non-small cell lung cancer: a feasibility study

Abstract Background The evaluation of circulating tumour DNA (ctDNA) from clinical blood samples, liquid biopsy, offers several diagnostic advantages compared with traditional tissue biopsy, such as shorter processing time, reduced patient risk and the opportunity to assess tumour heterogeneity. The...

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Bibliographic Details
Main Authors: G. M. Walls, L. McConnell, J. McAleese, P. Murray, T. B. Lynch, K. Savage, G. G. Hanna, D. Gonzalez de Castro
Format: Article
Language:English
Published: BMC 2020-05-01
Series:Radiation Oncology
Subjects:
ctDNA
Ultra-deep NGS
Radical radiotherapy
Lung cancer
Online Access:http://link.springer.com/article/10.1186/s13014-020-01583-7

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