Allergic bronchopulmonary aspergillosis

Allergic bronchopulmonary aspergillosis (ABPA) is an inflammatory disease caused by immunologic reactions initiated against Aspergillus fumigatus colonizing the airways of patients with asthma and cystic fibrosis. The common manifestations include treatment-resistant asthma, transient and fleeting p...

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Main Authors: Ritesh Agarwal, Inderpaul S Sehgal, Sahajal Dhooria, Valliappan Muthu, Kuruswamy T Prasad, Amanjit Bal, Ashutosh N Aggarwal, Arunaloke Chakrabarti
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2020-01-01
Series:Indian Journal of Medical Research
Subjects:
Online Access:http://www.ijmr.org.in/article.asp?issn=0971-5916;year=2020;volume=151;issue=6;spage=529;epage=549;aulast=Agarwal
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spelling doaj-682fe1ab73204a078821079d9156b1222020-11-25T03:25:53ZengWolters Kluwer Medknow PublicationsIndian Journal of Medical Research0971-59162020-01-01151652954910.4103/ijmr.IJMR_1187_19Allergic bronchopulmonary aspergillosisRitesh AgarwalInderpaul S SehgalSahajal DhooriaValliappan MuthuKuruswamy T PrasadAmanjit BalAshutosh N AggarwalArunaloke ChakrabartiAllergic bronchopulmonary aspergillosis (ABPA) is an inflammatory disease caused by immunologic reactions initiated against Aspergillus fumigatus colonizing the airways of patients with asthma and cystic fibrosis. The common manifestations include treatment-resistant asthma, transient and fleeting pulmonary opacities and bronchiectasis. It is believed that globally there are about five million cases of ABPA, with India alone accounting for about 1.4 million cases. The occurrence of ABPA among asthmatic patients in special clinics may be as high as 13 per cent. Thus, a high degree of suspicion for ABPA should be entertained while treating a patient with bronchial asthma, particularly in specialized clinics. Early diagnosis and appropriate treatment can delay (or even prevent) the onset of bronchiectasis, which suggests that all patients of bronchial asthma should be screened for ABPA, especially in chest clinics. The current review summarizes the recent advances in the pathogenesis, diagnosis and management of ABPA.http://www.ijmr.org.in/article.asp?issn=0971-5916;year=2020;volume=151;issue=6;spage=529;epage=549;aulast=Agarwalallergic bronchopulmonary aspergillosis - allergic bronchopulmonary mycosis - aspergillus - asthma - azole - cystic fibrosis - glucocorticoids
collection DOAJ
language English
format Article
sources DOAJ
author Ritesh Agarwal
Inderpaul S Sehgal
Sahajal Dhooria
Valliappan Muthu
Kuruswamy T Prasad
Amanjit Bal
Ashutosh N Aggarwal
Arunaloke Chakrabarti
spellingShingle Ritesh Agarwal
Inderpaul S Sehgal
Sahajal Dhooria
Valliappan Muthu
Kuruswamy T Prasad
Amanjit Bal
Ashutosh N Aggarwal
Arunaloke Chakrabarti
Allergic bronchopulmonary aspergillosis
Indian Journal of Medical Research
allergic bronchopulmonary aspergillosis - allergic bronchopulmonary mycosis - aspergillus - asthma - azole - cystic fibrosis - glucocorticoids
author_facet Ritesh Agarwal
Inderpaul S Sehgal
Sahajal Dhooria
Valliappan Muthu
Kuruswamy T Prasad
Amanjit Bal
Ashutosh N Aggarwal
Arunaloke Chakrabarti
author_sort Ritesh Agarwal
title Allergic bronchopulmonary aspergillosis
title_short Allergic bronchopulmonary aspergillosis
title_full Allergic bronchopulmonary aspergillosis
title_fullStr Allergic bronchopulmonary aspergillosis
title_full_unstemmed Allergic bronchopulmonary aspergillosis
title_sort allergic bronchopulmonary aspergillosis
publisher Wolters Kluwer Medknow Publications
series Indian Journal of Medical Research
issn 0971-5916
publishDate 2020-01-01
description Allergic bronchopulmonary aspergillosis (ABPA) is an inflammatory disease caused by immunologic reactions initiated against Aspergillus fumigatus colonizing the airways of patients with asthma and cystic fibrosis. The common manifestations include treatment-resistant asthma, transient and fleeting pulmonary opacities and bronchiectasis. It is believed that globally there are about five million cases of ABPA, with India alone accounting for about 1.4 million cases. The occurrence of ABPA among asthmatic patients in special clinics may be as high as 13 per cent. Thus, a high degree of suspicion for ABPA should be entertained while treating a patient with bronchial asthma, particularly in specialized clinics. Early diagnosis and appropriate treatment can delay (or even prevent) the onset of bronchiectasis, which suggests that all patients of bronchial asthma should be screened for ABPA, especially in chest clinics. The current review summarizes the recent advances in the pathogenesis, diagnosis and management of ABPA.
topic allergic bronchopulmonary aspergillosis - allergic bronchopulmonary mycosis - aspergillus - asthma - azole - cystic fibrosis - glucocorticoids
url http://www.ijmr.org.in/article.asp?issn=0971-5916;year=2020;volume=151;issue=6;spage=529;epage=549;aulast=Agarwal
work_keys_str_mv AT riteshagarwal allergicbronchopulmonaryaspergillosis
AT inderpaulssehgal allergicbronchopulmonaryaspergillosis
AT sahajaldhooria allergicbronchopulmonaryaspergillosis
AT valliappanmuthu allergicbronchopulmonaryaspergillosis
AT kuruswamytprasad allergicbronchopulmonaryaspergillosis
AT amanjitbal allergicbronchopulmonaryaspergillosis
AT ashutoshnaggarwal allergicbronchopulmonaryaspergillosis
AT arunalokechakrabarti allergicbronchopulmonaryaspergillosis
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