Preparation of MSZ Hydrogel and Its Treatment of Colitis

Preparation of MSZ Hydrogel and Its Treatment of Colitis

In order to control the release of mesalazine (MSZ) in the gastrointestinal tract to achieve better pharmacological effects in the colon, in this study, MSZ was added to hydroxypropyl-β-cyclodextrin (HP-β-CD) to form a water-soluble HP-β-CD/MSZ inclusion complex. Then, the inclusion compound was loa...

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Bibliographic Details
Main Authors: Yanhong Wu, Shangyong Li, Mengfei Jin, Dandan Li, Zihan Zhou, Haiqing Hou, Yantao Han
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-10-01
Series:Frontiers in Pharmacology
Subjects:
MSZ
HP-β-CD
ALG
CS
κ-Car
hydrogel
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.706401/full

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