Continual Trials Spontaneous Recognition Tasks in Mice: Reducing Animal Numbers and Improving Our Understanding of the Mechanisms Underlying Memory

Spontaneous recognition tasks are widely used as a laboratory measure of memory in animals but give rise to high levels of behavioral noise leading to a lack of reliability. Previous work has shown that a modification of the procedure to allow continual trials testing (in which many trials are run c...

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Bibliographic Details
Main Authors: Michele Chan, Madeline J. Eacott, David J. Sanderson, Jianfei Wang, Mu Sun, Alexander Easton
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-09-01
Series:Frontiers in Behavioral Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fnbeh.2018.00214/full