Standardized Astragalus Mongholicus Bunge-Curcuma Aromatica Salisb. Extract Efficiently Suppresses Colon Cancer Progression Through Gut Microbiota Modification in CT26-Bearing Mice

Standardized Astragalus Mongholicus Bunge-Curcuma Aromatica Salisb. Extract Efficiently Suppresses Colon Cancer Progression Through Gut Microbiota Modification in CT26-Bearing Mice

Altered gut microbiota and a damaged colon mucosal barrier have been implicated in the development of colon cancer. Astragalus mongholicus Bunge-Curcuma aromatica Salisb. (ACE) is a common herbal drug pair that widely used clinically to treat cancer. However, whether the anti-cancer effect of ACE is...

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Bibliographic Details
Main Authors:	Junfei Gu, Ruolan Sun, Qiaohan Wang, Fuyan Liu, Decai Tang, Xiangwei Chang
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2021-08-01
Series:	Frontiers in Pharmacology
Subjects:	colon cancer gut microbiota astragalus mongholicus bunge-curcuma aromatica salisb. intestinal barrier short-chain fatty acids SDF-1/CXCR4
Online Access:	https://www.frontiersin.org/articles/10.3389/fphar.2021.714322/full

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