Effectiveness of pre-operative anaemia screening and increased Tranexamic acid dose policies on outcomes following unilateral primary, elective total hip or knee replacement: a statistical analysis plan for an interrupted time series and regression discontinuity study [version 2; peer review: 2 approved]

Perioperative blood transfusion is associated with poorer postoperative outcomes following hip and knee replacement surgery. Evidence for the effectiveness of some measures aimed at reducing blood transfusions in this setting are limited and often rely on weak pre-post study designs. Quasi-experimen...

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Bibliographic Details
Main Authors: Ashley B. Scrimshire, Caroline Fairhurst, Catriona McDaid, David J. Torgerson
Format: Article
Language:English
Published: F1000 Research Ltd 2021-05-01
Series:F1000Research
Online Access:https://f1000research.com/articles/9-224/v2