Evaluating natural killer cell cytotoxicity against solid tumors using a microfluidic model

Evaluating natural killer cell cytotoxicity against solid tumors using a microfluidic model

Immunotherapies against solid tumors face additional challenges compared with hematological cancers. In solid tumors, immune cells and antibodies need to extravasate from vasculature, find the tumor, and migrate through a dense mass of cells. These multiple steps pose significant obstacles for solid...

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Bibliographic Details
Main Authors: Jose M. Ayuso, Regan Truttschel, Max M. Gong, Mouhita Humayun, Maria Virumbrales-Munoz, Ross Vitek, Mildred Felder, Stephen D. Gillies, Paul Sondel, Kari B. Wisinski, Manish Patankar, David J. Beebe, Melissa C. Skala
Format: Article
Language:English
Published: Taylor & Francis Group 2019-03-01
Series:OncoImmunology
Subjects:
natural killer cell
antibody-dependent cell cytotoxicity
solid tumor
microfluidics
organotypic model
Online Access:http://dx.doi.org/10.1080/2162402X.2018.1553477

Internet

http://dx.doi.org/10.1080/2162402X.2018.1553477

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