Evaluation of Glycosylated PTGS2 in Colorectal Cancer for NSAIDS-Based Adjuvant Therapy

Evaluation of Glycosylated PTGS2 in Colorectal Cancer for NSAIDS-Based Adjuvant Therapy

Observational/retrospective studies indicate that prostaglandin-endoperoxide synthase-2 (PTGS2) inhibitors could positively affect colorectal cancer (CRC) patients’ survival after diagnosis. To obtain an acceptable cost/benefit balance, the inclusion of PTGS2 inhibitors in the adjuvant set...

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Bibliographic Details
Main Authors: Roberta Venè, Delfina Costa, Raffaella Augugliaro, Sebastiano Carlone, Stefano Scabini, Gianmaria Casoni Pattacini, Maurizio Boggio, Simonetta Zupo, Federica Grillo, Luca Mastracci, Francesca Pitto, Simona Minghelli, Nicoletta Ferrari, Francesca Tosetti, Emanuele Romairone, Maria C. Mingari, Alessandro Poggi, Roberto Benelli
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Cells
Subjects:
prostaglandin-endoperoxide synthase-2/cyclooxygenase 2 (ptgs2/cox-2)
colorectal cancer (crc)
non-steroidal anti-inflammatory drugs (nsaids)
cancer-associated fibroblasts (caf)
interleukin-1 beta (il1β)
macrophages
Online Access:https://www.mdpi.com/2073-4409/9/3/683

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https://www.mdpi.com/2073-4409/9/3/683

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