Defining mesenchymal stromal cell (MSC)-derived small extracellular vesicles for therapeutic applications

Small extracellular vesicles (sEVs) from mesenchymal stromal/stem cells (MSCs) are transiting rapidly towards clinical applications. However, discrepancies and controversies about the biology, functions, and potency of MSC-sEVs have arisen due to several factors: the diversity of MSCs and their prep...

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Bibliographic Details
Main Authors: Kenneth W. Witwer, Bas W.M. Van Balkom, Stefania Bruno, Andre Choo, Massimo Dominici, Mario Gimona, Andrew F. Hill, Dominique De Kleijn, Mickey Koh, Ruenn Chai Lai, S. Alex Mitsialis, Luis A. Ortiz, Eva Rohde, Takashi Asada, Wei Seong Toh, Daniel J. Weiss, Lei Zheng, Bernd Giebel, Sai Kiang Lim
Format: Article
Language:English
Published: Taylor & Francis Group 2019-12-01
Series:Journal of Extracellular Vesicles
Subjects:
msc
sev
Online Access:http://dx.doi.org/10.1080/20013078.2019.1609206