Ethanol Exposure Induces Microglia Activation and Neuroinflammation through TLR4 Activation and SENP6 Modulation in the Adolescent Rat Hippocampus

The ethanol-induced toll-like receptor 4 (TLR4) signal activation of microglia and neuroinflammation are observed in both adolescent and adult rat brains, but the regulatory mechanisms of some TLR4 signaling-related factors in this process are still unclear. SUMO-specific protease 6 (SENP6) inhibits...

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Bibliographic Details
Main Authors: Qing Li, Dexiang Liu, Fang Pan, Cyrus S. H. Ho, Roger C. M. Ho
Format: Article
Language:English
Published: Hindawi Limited 2019-01-01
Series:Neural Plasticity
Online Access:http://dx.doi.org/10.1155/2019/1648736