Effects of Anti-Integrin Treatment With Vedolizumab on Immune Pathways and Cytokines in Inflammatory Bowel Diseases

Effects of Anti-Integrin Treatment With Vedolizumab on Immune Pathways and Cytokines in Inflammatory Bowel Diseases

Background and aimsDespite proven clinical efficacy of vedolizumab (VDZ) for inducing and maintaining remission in patients with Crohn’s disease (CD) and ulcerative colitis (UC), subgroups of patients have no therapeutic benefit from anti-α4β7 integrin therapy with VDZ. Within this study, we aimed t...

Full description

Bibliographic Details
Main Authors: Timo Rath, Ulrike Billmeier, Fulvia Ferrazzi, Michael Vieth, Arif Ekici, Markus F. Neurath, Raja Atreya
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-07-01
Series:Frontiers in Immunology
Subjects:
inflammatory bowel diseases
ulcerative colitis
Crohn’s disease
vedolizumab
RNA sequencing
integrin
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.01700/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2018.01700/full

Similar Items