The macrophage microtubule network acts as a key cellular controller of the intracellular fate of Leishmania infantum.

The parasitophorous vacuoles (PVs) that insulate Leishmania spp. in host macrophages are vacuolar compartments wherein promastigote forms differentiate into amastigote that are the replicative form of the parasite and are also more resistant to host responses. We revisited the biogenesis of tight-fi...

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Bibliographic Details
Main Authors: Sandrine Cojean, Valérie Nicolas, Vanessa Lievin-Le Moal
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-07-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://doi.org/10.1371/journal.pntd.0008396