The effect of prednisolone on the NSE- and CD-68-positive cells of the spleen

The aim of our research was to study the effect of prednisolone on the quantitative and morphological characteristics of NSE+ and CD-68+ cells in different functional zones of the spleen. During the morphometrical research we set up five morphotypes of NSE+-cells and four morphotypes of CD-68+ cells...

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Bibliographic Details
Main Authors: E М Luzikova, V E Sergeeva
Format: Article
Language:English
Published: Peoples’ Friendship University of Russia (RUDN University) 2009-12-01
Series:RUDN Journal of Medicine
Subjects:
Online Access:http://journals.rudn.ru/medicine/article/view/2562
Description
Summary:The aim of our research was to study the effect of prednisolone on the quantitative and morphological characteristics of NSE+ and CD-68+ cells in different functional zones of the spleen. During the morphometrical research we set up five morphotypes of NSE+-cells and four morphotypes of CD-68+ cells. It showed that CD-68+ cells of II type and NSE+-cells (II and IV types) are more sensitive to prednisolone. We came to the conclusion that there is a probability of identity of subpopulations I NSE+ and 2 CD-68+, II NSE+ and 4 CD-68+, III NSE+ and 4 CD-68+ because they are characterised by identical morphological indicators in norm and in experiment.
ISSN:2313-0245
2313-0261