Molecular determinants of the Ska-Ndc80 interaction and their influence on microtubule tracking and force-coupling

Errorless chromosome segregation requires load-bearing attachments of the plus ends of spindle microtubules to chromosome structures named kinetochores. How these end-on kinetochore attachments are established following initial lateral contacts with the microtubule lattice is poorly understood. Two...

Full description

Bibliographic Details
Main Authors: Pim J Huis in 't Veld, Vladimir A Volkov, Isabelle D Stender, Andrea Musacchio, Marileen Dogterom
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2019-12-01
Series:eLife
Subjects:
Ska
Online Access:https://elifesciences.org/articles/49539