Distribution of interleukin-1 receptor complex at the synaptic membrane driven by interleukin-1β and NMDA stimulation

<p>Abstract</p> <p>Interleukin-1β (IL-1β) is a pro-inflammatory cytokine that contributes to neuronal injury in various degenerative diseases, and is therefore a potential therapeutic target. It exerts its biological effect by activating the interleukin-1 receptor type I (IL-1RI) a...

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Bibliographic Details
Main Authors: Marinovich Marina, Cattabeni Flaminio, Galli Corrado L, Corsini Emanuela, Zianni Elisa, Boraso Mariaserena, Gardoni Fabrizio, Di Luca Monica, Viviani Barbara
Format: Article
Language:English
Published: BMC 2011-02-01
Series:Journal of Neuroinflammation
Online Access:http://www.jneuroinflammation.com/content/8/1/14