Identification and Physicochemical Characteristics of Temozolomide Process-Related Impurities

Identification and Physicochemical Characteristics of Temozolomide Process-Related Impurities

In this article the crystal structures of the starting material TZ-5 and the key intermediate TZ-6 of temozolomide (TZ-7), an anticancer therapeutic agent, are presented, together with their spectroscopic and thermal characteristics. Both compounds crystallize in the triclinic P-1 space group. X-ray...

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Bibliographic Details
Main Authors: Marta Łaszcz, Marek Kubiszewski, Łukasz Jedynak, Monika Kaczmarska, Łukasz Kaczmarek, Wojciech Łuniewski, Krzysztof Gabarski, Anna Witkowska, Krzysztof Kuziak, Maura Malińska
Format: Article
Language:English
Published: MDPI AG 2013-12-01
Series:Molecules
Subjects:
temozolomide intermediate
X-ray crystallography
nuclear magnetic resonance
high-performance liquid chromatography
Online Access:http://www.mdpi.com/1420-3049/18/12/15344

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http://www.mdpi.com/1420-3049/18/12/15344

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