Single-cell transcriptome analysis of lineage diversity in high-grade glioma

Single-cell transcriptome analysis of lineage diversity in high-grade glioma

Abstract Background Despite extensive molecular characterization, we lack a comprehensive understanding of lineage identity, differentiation, and proliferation in high-grade gliomas (HGGs). Methods We sampled the cellular milieu of HGGs by profiling dissociated human surgical specimens with a high-d...

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Main Authors: Jinzhou Yuan, Hanna Mendes Levitin, Veronique Frattini, Erin C. Bush, Deborah M. Boyett, Jorge Samanamud, Michele Ceccarelli, Athanassios Dovas, George Zanazzi, Peter Canoll, Jeffrey N. Bruce, Anna Lasorella, Antonio Iavarone, Peter A. Sims
Format: Article
Language:English
Published: BMC 2018-07-01
Series:Genome Medicine
Online Access:http://link.springer.com/article/10.1186/s13073-018-0567-9

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http://link.springer.com/article/10.1186/s13073-018-0567-9

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