CcpA-independent glucose regulation of lactate dehydrogenase 1 in Staphylococcus aureus.

CcpA-independent glucose regulation of lactate dehydrogenase 1 in Staphylococcus aureus.

Lactate Dehydrogenase 1 (Ldh1) is a key enzyme involved in Staphylococcus aureus NO·-resistance. Full ldh1-induction requires the presence of glucose, and mutants lacking the Carbon-Catabolite Protein (CcpA) exhibit decreased ldh1 transcription and diminished Ldh1 activity. The redox-regulator Rex r...

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Bibliographic Details
Main Authors: Adrianne K Crooke, James R Fuller, Markus W Obrist, Sarah E Tomkovich, Nicholas P Vitko, Anthony R Richardson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3544828?pdf=render

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http://europepmc.org/articles/PMC3544828?pdf=render

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