Evaluating the effect of type 2 diabetes mellitus on CYP450 enzymes and P-gp activities, before and after glycemic control: A protocol for a case–control pharmacokinetic study

Evaluating the effect of type 2 diabetes mellitus on CYP450 enzymes and P-gp activities, before and after glycemic control: A protocol for a case–control pharmacokinetic study

Cytochrome P450s (CYP450) family is one of the most critical factors in the metabolism process. Hence, the present study aims to characterize the activity of CYP1A2, CYP2B6, CYP2C9, CYP2C19, CYP2D6, CYP3A4/5, and P-glycoprotein (P-gp) pump in patients with type 2 diabetes (T2DM). This characterizati...

Full description

Bibliographic Details
Main Authors: Navid Neyshaburinezhad, Mohammadreza Rouini, Nooshin Shirzad, Alireza Esteghamati, Manouchehr Nakhjavani, Soha Namazi, Yalda H. Ardakani
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:MethodsX
Subjects:
Diabetes mellitus
Cytochrome P450
Metabolism
Personalized medicine
Online Access:http://www.sciencedirect.com/science/article/pii/S2215016120300728

Internet

http://www.sciencedirect.com/science/article/pii/S2215016120300728

Similar Items