Quantification of Drug Transport Function across the MultipleResistance-Associated Protein 2 (Mrp2) in Rat Livers

To understand the transport function of drugs across the canalicular membrane of hepatocytes, it would be important to measure concentrations in hepatocytes and bile. However, these concentration gradients are rarely provided. The aim of the study is then to measure these concentrations and define p...

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Bibliographic Details
Main Authors: Pierre Bonnaventure, Catherine M. Pastor
Format: Article
Language:English
Published: MDPI AG 2014-12-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:http://www.mdpi.com/1422-0067/16/1/135