A common molecular signature of patients with sickle cell disease revealed by microarray meta-analysis and a genome-wide association study.

A common molecular signature of patients with sickle cell disease revealed by microarray meta-analysis and a genome-wide association study.

A chronic inflammatory state to a large extent explains sickle cell disease (SCD) pathophysiology. Nonetheless, the principal dysregulated factors affecting this major pathway and their mechanisms of action still have to be fully identified and elucidated. Integrating gene expression and genome-wide...

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Bibliographic Details
Main Authors: Cherif Ben Hamda, Raphael Sangeda, Liberata Mwita, Ayton Meintjes, Siana Nkya, Sumir Panji, Nicola Mulder, Lamia Guizani-Tabbane, Alia Benkahla, Julie Makani, Kais Ghedira, H3ABioNet Consortium
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6034806?pdf=render

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http://europepmc.org/articles/PMC6034806?pdf=render

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