Metformin may adversely affect orthostatic blood pressure recovery in patients with type 2 diabetes: substudy from the placebo-controlled Copenhagen Insulin and Metformin Therapy (CIMT) trial

Metformin may adversely affect orthostatic blood pressure recovery in patients with type 2 diabetes: substudy from the placebo-controlled Copenhagen Insulin and Metformin Therapy (CIMT) trial

Abstract Background Metformin has been shown to have both neuroprotective and neurodegenerative effects. The aim of this study was to investigate the effect of metformin in combination with insulin on cardiovascular autonomic neuropathy (CAN) and distal peripheral neuropathy (DPN) in individuals wit...

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Bibliographic Details
Main Authors: Christian Stevns Hansen, Louise Lundby-Christiansen, Lise Tarnow, Christian Gluud, Christoffer Hedetoft, Birger Thorsteinsson, Bianca Hemmingsen, Niels Wiinberg, Simone B. Sneppen, Søren S. Lund, Thure Krarup, Sten Madsbad, Thomas Almdal, Bendix Carstensen, Marit E. Jørgensen, the CIMT study group
Format: Article
Language:English
Published: BMC 2020-09-01
Series:Cardiovascular Diabetology
Subjects:
Type 2 diabetes
Metformin
Autonomic neuropathy
Orthostatic blood pressure recovery
Complications
Peripheral neuropathy
Online Access:http://link.springer.com/article/10.1186/s12933-020-01131-3

Internet

http://link.springer.com/article/10.1186/s12933-020-01131-3

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