Ubiquitin-Like Proteasome System Represents a Eukaryotic-Like Pathway for Targeted Proteolysis in Archaea

Ubiquitin-Like Proteasome System Represents a Eukaryotic-Like Pathway for Targeted Proteolysis in Archaea

The molecular mechanisms of targeted proteolysis in archaea are poorly understood, yet they may have deep evolutionary roots shared with the ubiquitin-proteasome system of eukaryotic cells. Here, we demonstrate in archaea that TBP2, a TATA-binding protein (TBP) modified by ubiquitin-like isopeptide...

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Bibliographic Details
Main Authors: Xian Fu, Rui Liu, Iona Sanchez, Cecilia Silva-Sanchez, Nathaniel L. Hepowit, Shiyun Cao, Sixue Chen, Julie Maupin-Furlow
Format: Article
Language:English
Published: American Society for Microbiology 2016-05-01
Series:mBio
Online Access:http://mbio.asm.org/cgi/content/full/7/3/e00379-16

Internet

http://mbio.asm.org/cgi/content/full/7/3/e00379-16

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