CSP--a model for in vivo presentation of Plasmodium berghei sporozoite antigens by hepatocytes.

One target of protective immunity against the Plasmodium liver stage in BALB/c mice is represented by the circumsporozoite protein (CSP), and mainly involves its recognition by IFN-γ producing specific CD8+T-cells. In a previous in vitro study we showed that primary hepatocytes from BALB/c mice proc...

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Bibliographic Details
Main Authors: Saidou Balam, Jackeline F Romero, Silayuv E Bongfen, Philippe Guillaume, Giampietro Corradin
Format: Article
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3525584?pdf=render