YY1 Promotes Telomerase Activity and Laryngeal Squamous Cell Carcinoma Progression Through Impairment of GAS5-Mediated p53 Stability

YY1 Promotes Telomerase Activity and Laryngeal Squamous Cell Carcinoma Progression Through Impairment of GAS5-Mediated p53 Stability

Yin Yang 1 (YY1) is a key transcription factor that exerts functional roles in the cell biological process of various cancers. The current study aimed to elucidate the role and mechanism of YY1 in laryngeal squamous cell carcinoma (LSCC). YY1 mRNA and protein expression in human LSCC cell lines was...

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Bibliographic Details
Main Authors: Xudong Wei, Fenglei Liu, Xuelian Jiang, Xiaoyan Xu, Tianhao Zhou, Chengfang Kang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Oncology
Subjects:
Yin Yang 1
LncRNA growth arrest-specific 5
p300
p53
laryngeal squamous cell carcinoma
telomere length
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.692405/full

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https://www.frontiersin.org/articles/10.3389/fonc.2021.692405/full

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