YAP drives cutaneous squamous cell carcinoma formation and progression

YAP drives cutaneous squamous cell carcinoma formation and progression

Squamous cell carcinoma (SCC) can progress to malignant metastatic cancer, including an aggressive subtype known as spindle cell carcinoma (spSCC). spSCC formation involves epithelial-to-mesenchymal transition (EMT), yet the molecular basis of this event remains unknown. The transcriptional co-activ...

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Bibliographic Details
Main Authors: Zoé Vincent-Mistiaen, Ahmed Elbediwy, Hannah Vanyai, Jennifer Cotton, Gordon Stamp, Emma Nye, Bradley Spencer-Dene, Gareth J Thomas, Junhao Mao, Barry Thompson
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2018-09-01
Series:eLife
Subjects:
Hippo pathway
YAP
carcinoma
Online Access:https://elifesciences.org/articles/33304

Internet

https://elifesciences.org/articles/33304

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